Copper-based Catalysts


Copper-based Catalysts for Cross-Coupling Reactions (1999-2007)
  • Discovered synthetic protocols for the use of copper(I) complexes as catalysts for the cross-coupling of aryl halides with various nucleophiles.
  • Two of our complexes, Cu(phenanthroline)(PPh3)Br (Cat. No. 29-4000) and [Cu(phenanthroline)(PPh3)2]NO3 (Cat. No. 29-6000) are available from Strem Chemicals.

The hydroboration of phenyl vinyl sulfide with catecholborane (HBcat) and pinacolborane (HBpin) has been examined with a number of rhodium, complexes, all of which proceed with excellent regiocontrol in favour of the branched product…

Synthetic protocols using copper(l) catalysts for the formation of diaryl acetylenes, 1,3-enynes, benzofurans and indoles are described.

We report a method for the synthesis of vinyl sulfides using the soluble copper(I) catalyst [Cu(phen)(PPh3)(2)]NO3. The desired vinyl sulfides are obtained in good to excellent yields, with retention of stereochemistry. This protocol tolerates a wide…